Research Article
Nonalcoholic Fatty Liver Disease Relationship with Metabolic Syndrome in Class III Obesity Individuals
Table 5
Mean serum concentrations of MS and IR biochemical indicators according to the staging of NAFLD.
| |
Variables | The staging of NAFLD by liver biopsy |
Comparison of staging of NAFLD | value | | Steatosis () | Steatohepatitis without fibrosis () | Steatohepatitis with fibrosis () |
| |
Glucose (mg/dL) |
98.0 ± 12.4 |
91.5 ± 19.2 |
102.3 ± 12.0 | Steatosis × steatohepatitis without fibrosis | 0.395 | | Steatosis × steatohepatitis with fibrosis | 0.432 | | Steatohepatitis without fibrosis × steatohepatitis with fibrosis | 0.553 |
| |
Insulin (mcU/mL) |
16.7 ± 7.4 |
20.5 ± 13.2 |
24.0 ± 4.2 | Steatosis × steatohepatitis without fibrosis | 0.235 | | Steatosis × steatohepatitis with fibrosis | 0.044 | | Steatohepatitis without fibrosis × steatohepatitis with fibrosis | 0.874 |
| |
HOMA-IR |
3.7 ± 1.7 |
5.6 ± 6.1 |
6.4 ± 1.8 | Steatosis × steatohepatitis without fibrosis | 0.202 | | Steatosis × steatohepatitis with fibrosis | 0.076 | | Steatohepatitis without fibrosis × steatohepatitis with fibrosis | 0.239 |
| |
TG (mg/dL) |
118.1 ± 41.5 |
159.5 ± 43.3 |
181.5 ± 46.6 | Steatosis × steatohepatitis without fibrosis | 0.570 | | Steatosis × steatohepatitis with fibrosis | 0.001 | | Steatohepatitis without fibrosis × steatohepatitis with fibrosis | 0.437 |
| |
HDL-c (mg/dL) |
48.9 ± 12.3 |
42.9 ± 9.0 |
38.9 ± 7.2 | Steatosis × steatohepatitis without fibrosis | 0.307 | | Steatosis × steatohepatitis with fibrosis | 0.038 | | Steatohepatitis without fibrosis × steatohepatitis with fibrosis | 0.374 |
|
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Mean and standard deviation; HDL-c: high-density lipoprotein cholesterol; HOMA-IR: homeostatic model assessment; TG: triglycerides.
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