Research Article
Clinical Significance of Cannabinoid Receptors CB1 and CB2 Expression in Human Malignant and Benign Thyroid Lesions
Table 2
Associations of CB1 and CB2 expression with clinicopathological characteristics in 44 patients with malignant thyroid lesions.
| Clinicopathological characteristics | CB1 expression | CB2 expression | Low | High | value | Low | High | value |
| | 21 (48%) | 23 (52%) | | 20 (45%) | 24 (55%) | | Age (mean SD; yrs) | | | | | | 0.7201 | Gender | | | 0.2021 | | | 0.9456 | Female | 15 (34%) | 20 (45%) | | 16 (36%) | 19 (43%) | | Male | 6 (14%) | 3 (7%) | | 4 (9%) | 5 (12%) | | Tumor size (T) | | | 0.6011 | | | 0.4844 | T1 | 15 (34%) | 18 (41%) | | 16 (36%) | 17 (39%) | | T2–4 | 6 (14%) | 5 (11%) | | 4 (9%) | 7 (16%) | | Lymph node metastasis (N) | | | 0.7132 | | | 0.0301 | N0 | 19 (43%) | 20 (45%) | | 20 (45%) | 19 (43%) | | N1 | 2 (5%) | 3 (7%) | | 0 (0%) | 5 (12%) | | Capsular invasion | | | 0.8250 | | | 0.1165 | No | 17 (39%) | 18 (41%) | | 18 (41%) | 17 (39%) | | Yes | 4 (9%) | 5 (11%) | | 2 (4%) | 7 (16%) | | Lymphatic invasion | | | 0.5220 | | | 0.1989 | No | 18 (41%) | 18 (41%) | | 18 (41%) | 18 (41%) | | Yes | 3 (7%) | 5 (11%) | | 2 (4%) | 6 (14%) | | Vascular invasion | | | 0.3398 | | | 0.0555 | No | 20 (45%) | 20 (45%) | | 20 (45%) | 20 (45%) | | Yes | 1 (3%) | 3 (7%) | | 0 (0%) | 4 (10%) | | Ki-67 protein statement | | | 0.5827 | | | 0.2828 | Below mean value | 12 (27%) | 15 (34%) | | 14 (32%) | 13 (30%) | | Over mean value | 9 (21%) | 8 (18%) | | 6 (14%) | 11 (25%) | |
|
|