The Potential Role of Polymethyl Methacrylate as a New Packaging Material for the Implantable Medical Device in the Bladder

Table 1

The changes of macrophages and MIF in the bladder.

	1 week	2 weeks	4 weeks
Control
Macrophages (pg/mL)	1.0 ± 0.07	0.9 ± 0.08	0.9 ± 0.08
MIF (pg/mL)	211.0 ± 0.06	269.5 ± 0.01	308 ± 0.02
Sham-operation
Macrophages (pg/mL)	1.3 ± 0.08	1.0 ± 0.1	1.2 ± 0.06
MIF (pg/mL)	209.0 ± 0.07	298.0 ± 0.03	305.3 ± 0.02
PDMS-coating
Macrophages (pg/mL)		3.6 ± 0.05	1.5 ± 0.05
MIF (pg/mL)		599.7 ± 0.13	458.3 ± 0.08
PMMA-coating
Macrophages (pg/mL)		2.8 ± 0.05	1.8 ± 0.01
MIF (pg/mL)		605.5 ± 0.24	540 ± 0.05

compared with the control, compared with sham-operation.