Research Article
The Potential Role of Polymethyl Methacrylate as a New Packaging Material for the Implantable Medical Device in the Bladder
Table 2
The changes of inflammatory cytokines, IL-1β, IL-6, and TNF-α, in the bladder.
| | | 1 week | 2 weeks | 4 weeks |
| | Control | | | | | IL-1β (pg/mL) | 85.7 ± 0.02 | 83.5 ± 0.01 | 84.9 ± 0.01 | | IL-6 (pg/mL) | 253.8 ± 0.05 | 322.1 ± 0.01 | 302.9 ± 0.01 | | TNF-α (pg/mL) | 42.0 ± 0.01 | 38.4 ± 0.01 | 37.4 ± 0.02 | | Sham-operation | | | | | IL-1β (pg/mL) | 84.0 ± 0.02 | 85.3 ± 0.03 | 86.0 ± 0.01 | | IL-6 (pg/mL) | 249.3 ± 0.03 | 308.9 ± 0.01 | 311.7 ± 0.05 | | TNF-α (pg/mL) | 39.6 ± 0.02 | 40.1 ± 0.03 | 38.7 ± 0.01 | | PDMS-coating | | | | | IL-1β (pg/mL) | | 240.4 ± 0.01 | 148.7 ± 0.02 | | IL-6 (pg/mL) | | 515.7 ± 0.02 | 388.2 ± 0.03 | | TNF-α (pg/mL) | | 70.5 ± 0.01 | 47.2 ± 0.02 | | PMMA-coating | | | | | IL-1β (pg/mL) | | 189.7 ± 0.04 | 150.1 ± 0.01 | | IL-6 (pg/mL) | | 548.2 ± 0.01 | 389.4 ± 0.04 | | TNF-α (pg/mL) | | 62.8 ± 0.23 | 48.5 ± 0.09 |
|
|
compared with the control, compared with sham-operation.
|
