Research Article

Variants of SCARB1 and VDR Involved in Complex Genetic Interactions May Be Implicated in the Genetic Susceptibility to Clear Cell Renal Cell Carcinoma

Table 4

Results of multivariate binary logistic regression analysis concerning all SNPs under study, haplotypes, and disclosed interactions.

Multivariate binary logistic regression analysis
Variables in the modelGenesOR (95% CI) value of variable in the model

Haplotype CAGT (rs739837-rs731236-rs7975232-rs1544410)VDR cs0.005
rs4765623rs9679290SCARB1EPAS1 1.389 (1.094–1.763)0.007
MC1R “r”rs7975232MC1RVDR 1.455 (1.095–1.933)0.010
rs7121rs2228570GNAS1VDR 1.238 (1.009–1.518)0.041