Flax Fiber Hydrophobic Extract Inhibits Human Skin Cells Inflammation and Causes Remodeling of Extracellular Matrix and Wound Closure Activation

Figure 3

NHEK cells after treatments with flax fiber cannabinoid extract. C: control untreated cells; EtOH: cells after 24-hour incubation with ethanol, the negative control; Ex 1: cells treated with the extract where final CBD concentration was 0.211 μg/mL of culture; Ex 2: cells after incubation with extract diluted twice with ethanol, 0.105 μg CBD/mL of culture; Ex 5: cells incubated with five times diluted Ex 1, CBD concentration 0.042 μg/mL; CBD 1, CBD 2, and CBD 5: cells treated with pure CBD standard, final concentration analogical to Ex 1, 2, and 5, respectively, used as positive controls. Images on the left side show the cells of each sample growing in a large confluence, while the ones on the right represent the same sample but in a region of lower growth density.