Hypoglycaemia, Abnormal Lipids, and Cardiovascular Disease among Chinese with Type 2 Diabetes
Table 2
Odds ratio of abnormal lipids for mild and severe hypoglycaemia.
Mild hypoglycaemia
Severe hypoglycaemia
Either mild or severe hypoglycaemia
OR (95% CI)
value
OR (95% CI)
value
OR (95% CI)
value
Model one
LDL-C, mmol/L
1.12 (1.00–1.26)
0.0526
1.22 (1.05–1.43)
0.0139
1.14 (1.03–1.26)
0.0109
HDL-C, mmol/L
1.12 (1.00–1.26)
0.0526
1.22 (1.05–1.43)
0.0139
1.14 (1.03–1.26)
0.0109
Triglyceride, mmol/L
1.12 (1.05–1.19)
0.0002
1.02 (0.87–1.19)
0.7988
1.10 (1.05–1.17)
0.0005
Model two
LDL-C, mmol/L
1.14 (1.01–1.29)
0.0331
1.21 (1.04–1.17)
0.0163
1.15 (1.03–1.28)
0.0110
HDL-C, mmol/L
1.10 (1.04–1.17)
0.0015
1.01 (0.87–1.17)
0.8922
1.09 (1.03–1.16)
0.0049
Triglyceride, mmol/L
0.96 (0.86–1.07)
0.4664
1.10 (0.94–1.28)
0.2313
0.98 (0.89–1.09)
0.7388
Model three
LDL-C, mmol/L
1.14 (1.01–1.29)
0.0340
1.24 (1.05–1.48)
0.0129
1.17 (1.04–1.31)
0.0079
HDL-C, mmol/L
1.10 (1.03–1.17)
0.0030
1.02 (0.83–1.24)
0.8860
1.09 (1.02–1.16)
0.0084
Triglyceride, mmol/L
0.92 (0.82–1.04)
0.1858
1.02 (0.82–1.26)
0.8916
0.93 (0.83–1.04)
0.2238
Model one: not adjusted for other variables. Model two: adjusted for age, sex, BMI, HbA1c, systolic BP, and log-transformed urinary albumin to creatinine ratio. Model three: further adjusted for diabetes complications (coronary artery disease, stroke, and peripheral arterial disease) and drug use (statins, other lipid lowering drugs, rennin-angiotensin system inhibitors, oral antidiabetes drugs only, glucagon-like peptide-1 based treatment, basal insulin based treatment, and premixed insulin based treatment).
