Research Article

15d-PGJ2 Reduced Microglia Activation and Alleviated Neurological Deficit of Ischemic Reperfusion in Diabetic Rat Model

Table 3

Evaluation of microglia activation.

GroupCD68 positive area (μm2)
24 hours after reperfusion7 days after reperfusion

Sham-operated group 203 ± 45.40196 ± 102.70

Standard ischemia group 662 ± 112.56574 ± 134.20
Diabetic ischemia group 856 ± 178.09743 ± 205.67
Diabetic ischemia group and treated with 15d-PGJ2 587 ± 155.65405 ± 98.62

Note: △ indicates value is less than 0.05 when compared with sham-operated group; indicates value is less than 0.05 when compared with standard ischemia group; ▲ indicates value is less than 0.05 when compared with diabetic ischemia group.