Clinical Study

Rebamipide Improves Chronic Inflammation in the Lesser Curvature of the Corpus after Helicobacter pylori Eradication: A Multicenter Study

Table 2

Comparison of histological gastritis before and after H. pylori eradication in the rebamipide group.

Before eradicationAfter eradication value

GC of the middle antrum Activity1.00 ± 0.12 (48)0.00 ± 0.00 (47)<0.0001
Inflammation2.44 ± 0.10 (48)1.21 ± 0.08 (47)<0.0001
Atrophy1.27 ± 0.07 (48)0.96 ± 0.10 (47)0.0270
Intestinal metaplasia0.69 ± 0.16 (48)0.43 ± 0.11 (47)0.0887

GC of the middle corpusActivity1.08 ± 0.11 (49)0.02 ± 0.01 (47)<0.0001
Inflammation2.24 ± 0.09 (49)1.11 ± 0.10 (47)<0.0001
Atrophy0.90 ± 0.09 (49)0.34 ± 0.08 (47)<0.0001
Intestinal metaplasia0.14 ± 0.09 (49)0.19 ± 0.09 (47)0.5039

LC of the middle corpus Activity1.00 ± 0.11 (48)0.00 ± 0.00 (49)<0.0001
Inflammation2.29 ± 0.10 (48)1.12 ± 0.08 (49)<0.0001
Atrophy1.17 ± 0.09 (48)0.71 ± 0.10 (49)0.0005
Intestinal metaplasia0.85 ± 0.17 (48)0.84 ± 0.16 (49)0.6950

Data are presented as mean ± standard error (). GC: greater curvature and LC: lesser curvature.