Research Article
Evaluation of Influence of Various Polymers on Dissolution and Phase Behavior of Carbamazepine-Succinic Acid Cocrystal in Matrix Tablets
Table 4
Physical evaluation of CBZ tablets.
| | Formulation | Weight (mg) | Thickness (mm) | Hardness (N) | Diameter (mm) |
| | CH-1 | 444.64 ± 2.51 | 4.71 ± 0.02 | 198.47 ± 3.50 | 10.01 ± 0.00 | | CH-2 | 320.24 ± 2.60 | 4.28 ± 0.01 | 195.38 ± 6.60 | 10.00 ± 0.01 | | CH-3 | 258.18 ± 1.53 | 4.01 ± 0.03 | 192.72 ± 4.91 | 10.02 ± 0.01 | | CS-1 | 440.49 ± 2.13 | 4.64 ± 0.01 | 207.95 ± 4.36 | 10.02 ± 0.01 | | CS-2 | 322.25 ± 1.61 | 4.20 ± 0.01 | 209.45 ± 2.90 | 10.00 ± 0.01 | | CS-3 | 262.91 ± 0.01 | 3.84 ± 0.01 | 201.09 ± 3.53 | 9.99 ± 0.15 | | CK-1 | 449.02 ± 0.50 | 4.76 ± 0.03 | 194.46 ± 4.67 | 10.02 ± 0.01 | | CK-2 | 317.09 ± 3.16 | 4.22 ± 0.01 | 199.24 ± 6.10 | 10.01 ± 0.01 | | CH-3 | 260.11 ± 1.00 | 3.89 ± 0.01 | 203.16 ± 4.32 | 10.03 ± 0.01 |
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