Activity of BKM120 and BEZ235 against Lymphoma Cells

Figure 11

We quantitatively determined p62 expression (a) and apoptosis (based on caspase-3 expression) (b) in PBMCs from patients and donors. We evaluated the effects of BKM120 and BEZ235 on PBMCs from three patients with mantle cell lymphoma (MCL), four patients with follicular cell lymphoma (FCL), two patients with T-cell lymphoma (TCL), and four healthy donors (HD). Results represent the mean ± SD.

(a)

(b)