Extraction Optimization for Obtaining Artemisia capillaris Extract with High Anti-Inflammatory Activity in RAW 264.7 Macrophage Cells

Table 3

Optimal extraction conditions determined by superimposing the response surfaces for extracts from Artemisia capillaris Thunb.

Independent variables	Optional condition; (predicted ranges)	Predicted value		Experimental value
			61 (57–65)	53.87	56.16	52.65 ± 1.01	57.55 ± 1.23
	51 (45–57)
	6.2 (5.5–6.8)

: extraction temperature (°C).
²: ethanol concentration (%).
³: extraction time (h).
⁴: LPS-induced PGE₂ production (%).
⁵: LPS-induced NO production (%).