Research Article

Preoperative Neutrophil-to-Lymphocyte Ratio and Neutrophilia Are Independent Predictors of Recurrence in Patients with Localized Papillary Renal Cell Carcinoma

Table 1

Clinical and pathological characteristics of 218 pRCC patients stratified according to NLR.

VariablesNumber of Pts (%)NLR ≥ 3.6NLR < 3.6 value

Patients, (%)21876 (34.9)142 (65.1) 
Age (years), mean ± SD58.9 ± 12.259.7 ± 11.658.5 ± 12.50.460
Gender   0.712
 Male169 (77.5)60 (78.9)109 (76.8)
 Female49 (22.5)16 (21.1)33 (23.2)
Symptoms at presentation   0.140
 Symptom37 (17.0)9 (11.8)28 (19.7)
 Asymptomatic181 (83.0)67 (88.2)114 (80.3)
Hypertension   0.053
 Yes91 (41.7)25 (32.9)66 (46.5)
 No127 (58.3)51 (67.1)76 (53.5)
Diabetes mellitus   0.431
 Yes22 (10.1)6 (7.9)16 (11.3)
 No196 (89.9)70 (92.1)126 (88.7)
Tumor size (cm), median (IQR)3.5 (2.5–6.0)4.0 (3.0–7.0)3.2 (2.1–5.0)0.005
T stage   0.290
 T1160 (73.4)52 (68.4)108 (76.1)
 T220 (9.2)10 (13.2)10 (7.0)
 T338 (19.5)14 (18.4)24 (16.9)
N stage   0.097
 N17 (3.2)5 (6.6)2 (1.4)
 N0211 (96.8)71 (93.4)140 (98.6)
Fuhrman grade   0.763
 1-2155 (71.1)55 (72.4)100 (70.4)
 3-463 (28.9)21 (27.6)42 (29.6)
pRCC type   0.079
 1 type126 (57.8)38 (51.4)88 (63.8)
 2 type86 (39.4)36 (48.6)50 (36.2)
Unknown6 (2.8)
Tumor necrosis   0.653
 Yes34 (15.6)13 (17.1)21 (14.8)
 No184 (84.4)63 (82.9)121 (85.2)