Research Article
Comparative Analysis of Methods to Induce Myocardial Infarction in a Closed-Chest Rabbit Model
Table 2
Distribution and follow-up depending on embolization device.
| Embolization device () | Intraoperative events | 3-week survival () | Echographic assessment | Histologic assessment |
| Free coil | | | | | CA () | VF | 0 | — | Transmural infarct | RCA () | VF | 0 | — | Transmural infarct | Interlocking coil | | | | | CA () | VF | 1 | LVEF decrease <15% | Nontransmural infarct | RCA () | VF | 1 | No dysfunction | No infarct | Gelatin sponge | | | | | CA () | — | 3 | No dysfunction | Nontransmural infarct | RCA () | — | 1 | No dysfunction | No infarct | Balloon occlusion | | | | | CA () | NSVT | 2 | No dysfunction | No infarct | RCA () | NSVT | 2 | No dysfunction | No infarct | Alcoholization | | | | | CA () | VF | 4 | 15% decrease in LVEF | Transmural infarct | RCA () | CHF | 2 | RV dysfunction 15% decrease in LVEF | Transmural infarct |
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CA: circumflex artery; RCA: right coronary artery; LV: left ventricle; RV: right ventricle; VF: ventricular fibrillation; NSVT: nonsustained ventricular tachycardia; CHF: congestive heart failure.
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