MUTYH Gene Polymorphisms as Risk Factors for Rheumatoid Arthritis
Table 4
Frequencies of rs3219463 genotypes of RA patients with various clinical features.
rs3219463 genotype
RF
Extra-articular
Erosion
rs3219476 genotype
RF
Extra-articular
Erosion
(%)
(%)
(%)
(%)
(%)
(%)
G/− ()
126 (75.9)
81 (48.8)
83 (50.0)
T/− ()
119 (72.1)
75 (45.5)
87 (52.7)
A/A ()
14 (53.8)
10 (38.5)
14 (53.8)
G/G ()
22 (81.5)
16 (59.3)
10 (37.0)
P
0.019*
0.326
0.715
0.307
0.183
0.131
OR
2.700
1.525
0.857
OR
0.588
0.573
1.896
95% CI
1.155–6.312
0.654–3.556
0.374–1.964
95% CI
0.21–1.65
0.25–1.31
0.82–4.39
A/− ()
109 (70.3)
76 (49.0)
79 (51.0)
G/− ()
120 (75.5)
77 (48.4)
77 (48.4)
G/G ()
31 (83.8)
15 (40.5)
18 (48.6)
T/T ()
21 (63.6)
14 (42.4)
20 (60.6)
P
0.098
0.353
0.800
0.161
0.530
0.203
OR
0.459
1.411
1.097
OR
1.758
1.274
0.610
95% CI
0.179–1.174
0.681–2.2922
0.535–2.249
95% CI
0.79–3.90
0.60–2.72
0.28–1.31
95% CI: 95% confidence intervals. OR: odds ratio. value of <0.05 was determined as statistically significant. The chi-square test was performed to obtain the value. RF: rheumatoid factors.
