Review Article

The Roles of Hedgehog Signaling in Upper Lip Formation

Figure 2

The expression of Shh and Patched1 during the growth of facial processes in mouse embryos. ((a), (c), and (e)) In situ hybridization of Shh on E10 and E11.0. (b) In situ hybridization of Patched1 on E10. ((d) and (f)) LacZ staining of E11.0 Patched1-LacZ mice. (g) LacZ staining of a Topgal mouse embryo on E11.0. The red arrowheads indicate the position of the frontonasal ectodermal zone (FEZ).