Assessment of Functional Characteristics of Amnestic Mild Cognitive Impairment and Alzheimer’s Disease Using Various Methods of Resting-State FMRI Analysis

Table 9

Results of post hoc two-sample -tests between every pair of the healthy subjects and patients with AD and aMCI groups in GBC approach.

Brain regions	R/L	Coordinates; (mm)			Peak; value	Voxels
		Healthy subject versus aMCI
Superior frontal gyrus	R	2	2	58	4.26	525
Postcentral gyrus	L	−20	−52	66	4.04	207
Precentral gyrus	L	−48	−4	12	3.59	162
Middle temporal gyrus	L	−40	−58	10	5.88	158
Superior temporal gyrus	L	−50	−42	14	4.19	154
Transverse temporal gyrus	L	−50	−24	12	3.77	143
Cingulate gyrus	L	−12	−14	40	4.06	136
aMCI versus AD
Cerebellum	L	−28	−48	−52	3.65	141
Healthy subject versus AD
Superior temporal gyrus	L	−68	−24	6	4.36	258
Cerebellum	L	−28	−46	−48	4.48	246
ACC	L	−2	12	28	5.53	241
Cingulate gyrus	R	16	−20	40	5.09	165
Parahippocampal gyrus,	L	−36	−28	−12	4.07	153
Superior temporal gyrus	L	−38	−58	12	130	130

ACC: anterior cingulate gyrus. Positive values: healthy subjects > aMCI, aMCI > AD, and healthy subjects > AD. Negative values: aMCI > healthy subjects, AD > aMCI, and AD > healthy subjects. Threshold: corrected < 0.05.