Research Article

A Versatile Orthotopic Nude Mouse Model for Study of Esophageal Squamous Cell Carcinoma

Figure 2

Orthotopic ESCC cell line model. (a) Different cell numbers were evaluated for orthotopic tumor formation for four ESCC cell lines. (b) Xenogen images of 105 cells for four ESCC cell lines expressing luciferase illustrate the growth of the tumor with (A) KYSE150 luc, (B) KYSE30 luc, (C) 81-T luc, and (D) SLMT-1 luc. (c) The bioluminescence live animal images displaying coronal, sagittal, and transaxial cross-section views of the animal and providing tumor depth and location information of a KYSE150 orthotopic tumor in 3D taken by the Xenogen IVIS Spectrum.
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