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BioMed Research International
Volume 2015, Article ID 914026, 6 pages
Research Article

Lentiviral-Mediated Silencing of Farnesyl Pyrophosphate Synthase through RNA Interference in Mice

Institute of Cardiology, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou 310003, China

Received 23 May 2014; Revised 6 December 2014; Accepted 2 January 2015

Academic Editor: Min Li

Copyright © 2015 Jian Yang et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Supplementary Material

In order to determine whether the expression of the FPPS transgene caused any pathological changes, we made pathological analysis on various tissues including intestine, liver, heart, lung, spleen, muscle, kidney and brain. As shown in Supplementary figure 1, there were no obvious pathological changes in the tissues examined.

  1. Supplementary Material