Research Article

Lentiviral-Mediated Silencing of Farnesyl Pyrophosphate Synthase through RNA Interference in Mice

Table 1

Sequences of five siRNAs targeting murine FPPS and one nontargeting control.

Vector GeneTarget sequenceGC%

pLVT202FPPSGACAGCTTTCTACTCTTTC42.1
pLVT274FPPSCGCCAGATCTTAGAGGAGAAT 47.6
pLVT275FPPSGCTTTCTTCAAGTATGAGGAA38.1
pLVT276FPPSGCCATGTGGATCTTGGTAGAT47.6
pLVT277FPPSGCTTTCTTCCTTGTGTCAGAT42.9
pLVT7NCTTCTCCGAACGTGTCACGT52.6

NC: nontargeting control.