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BioMed Research International
Volume 2015 (2015), Article ID 915185, 8 pages
http://dx.doi.org/10.1155/2015/915185
Research Article

Diagnostic Accuracy of Obstructive Airway Adult Test for Diagnosis of Obstructive Sleep Apnea

1Maxillo Facial Surgery, Complesso Integrato Columbus, Catholic University Medical School, Rome, Italy
2Special Surgery Department, Ear-Nose-Throat Unit, Morgagni-Pierantoni Hospital, Forlì, Italy
3Department of Otolaryngology Head and Neck Surgery, Hospital Fazzi, Lecce, Italy
4Department of Otolaryngology, S. Pio X Hospital, Milan, Italy
5Department of Otolaryngology Head and Neck Surgery, S. Orsola-Malpighi University Hospital, Bologna, Italy
6Department of Medical, Oral and Biotechnological Sciences, University of Chieti-Pescara, Chieti, Italy
7Department of Periodontology, Catholic University of the Sacred Heart, Rome, Italy
8“A. Galateo” Respiratory Rehabilitation Unit, San Cesario di Lecce, Italy
9Department of Neurology, Complesso Integrato Columbus, Rome, Italy

Received 7 April 2015; Revised 6 July 2015; Accepted 9 August 2015

Academic Editor: Fabrizio Montecucco

Copyright © 2015 Giulio Gasparini et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Rationale. The gold standard for the diagnosis of Obstructive Sleep Apnea (OSA) is polysomnography, whose access is however reduced by costs and limited availability, so that additional diagnostic tests are needed. Objectives. To analyze the diagnostic accuracy of the Obstructive Airway Adult Test (OAAT) compared to polysomnography for the diagnosis of OSA in adult patients. Methods. Ninety patients affected by OSA verified with polysomnography (AHI ≥ 5) and ten healthy patients, randomly selected, were included and all were interviewed by one blind examiner with OAAT questions. Measurements and Main Results. The Spearman rho, evaluated to measure the correlation between OAAT and polysomnography, was 0.72 (). The area under the ROC curve (95% CI) was the parameter to evaluate the accuracy of the OAAT: it was 0.91 (0.81–1.00) for the diagnosis of OSA (AHI ≥ 5), 0.90 (0.82–0.98) for moderate OSA (AHI ≥ 15), and 0.84 (0.76–0.92) for severe OSA (AHI ≥ 30). Conclusions. The OAAT has shown a high correlation with polysomnography and also a high diagnostic accuracy for the diagnosis of OSA. It has also been shown to be able to discriminate among the different degrees of severity of OSA. Additional large studies aiming to validate this questionnaire as a screening or diagnostic test are needed.