BioMed Research International

Review Article

Transcriptome and Molecular Endocrinology Aspects of Epicardial Adipose Tissue in Cardiovascular Diseases: A Systematic Review and Meta-Analysis of Observational Studies

Table 1

Gene enrichment and functional annotation analysis (top ten significantly enriched GO terms with a high count of DEGs in the EAT samples).
GO_idFunctional termEnrichment score valueFDR  
value
0043066Negative regulation of apoptosis8.3563483187861273.95 × 10−96.51 × 10−6
0042981Regulation of apoptosis6.5110952103548662.82 × 10−74.64 × 10−4
0051090Regulation of transcription factor activity5.8084583036157815.23 × 10−78.62 × 10−4
0003044Regulation of systemic arterial blood pressure mediated by a chemical signal5.1169256477424791.09 × 10−60.001802
0006873Cellular ion homeostasis4.7047928123431221.12 × 10−50.018473
0051223Regulation of protein transport4.5191569480569492.02 × 10−50.033305
0051091Positive regulation of transcription factor activity4.3091754704784012.84 × 10−50.046671
0030335Positive regulation of cell migration3.7666913510476391.33 × 10−40.219528
0030334Regulation of cell migration3.70197151025792651.32 × 10−40.21785
0016477Cell migration3.400045104434131.46 × 10−40.240623