Piloting the Impact of Three Interventions on Guaiac Faecal Occult Blood Test Uptake within the NHS Bowel Cancer Screening Programme

Table 4

Modelled absolute and relative differencesⁱ in gFOBT uptake across the intervention groupsⁱⁱ overall and within different previous screening status groups.

	() Analysis of 60–69-year-olds						() Analysis of 70–74-year-olds
Previous screening status	Control group; ( = 145,427)	(A) CRUK endorsement flyer only; ( = 8,093)	(B) CRUK endorsement flyer, plus kit enhancement pack; ( = 7,148)	(C) CRUK endorsement flyer, plus advertising campaign; ( = 4,332)	(D) CRUK endorsement flyer, plus kit enhancement pack and advertising campaign; ( = 3,980)		Control group; ( = 31,959)	(A) CRUK endorsement flyer only; ( = 1,609)	(B) CRUK endorsement flyer, plus kit enhancement pack; ( = 1,475)	(C) CRUK endorsement flyer, plus advertising campaign; ( = 466)	(D) CRUK endorsement flyer, plus kit enhancement pack and advertising campaign; ( = 1,052)
Predicted probability of uptake in each intervention group and control group
Overall	43.4%	43.0%	45.1%	45.6%	49.5%		46.7%	45.1%	47.3%	43.6%	53.9%
Previously screened	79.3%	79.0%	80.4%	80.7%	83.0%		78.5%	77.4%	78.9%	76.4%	83.0%
First-timers	33.7%	33.4%	35.3%	35.7%	39.4%		29.9%	28.6%	30.4%	27.4%	36.3%
Previous nonresponders	12.5%	12.3%	13.3%	13.5%	15.4%		11.1%	10.5%	11.3%	9.9%	14.3%
Absolute difference in modelled uptake in each significant intervention group, compared to control group
Overall	43.4%	—	+1.7%	+2.2%	+6.1%		46.7%	—	—	—	+7.3%
Previously screened	79.3%	—	+1.1%	+1.4%	+3.8%		78.5%	—	—	—	+4.5%
First-timers	33.7%	—	+1.6%	+2.0%	+5.7%		29.9%	—	—	—	+6.4%
Previous nonresponders	12.5%	—	+0.8%	+1.0%	+3.0%		11.1%	—	—	—	+3.2%
Relative difference in modelled uptake in each significant intervention group, compared to control group
Overall	43.4%	—	+4.0%	+5.0%	+14.2%		46.7%	—	—	—	+15.6%
Previously screened	79.3%	—	+1.4%	+1.8%	+4.8%		78.5%	—	—	—	+5.7%
First-timers	33.7%	—	+4.7%	+5.9%	+17.0%		29.9%	—	—	—	+21.5%
Previous nonresponders	12.5%	—	+6.3%	+7.9%	+23.7%		11.1%	—	—	—	+28.9%

Data shows the predicted probability of uptake using multivariate logistic regression models, after accounting for other factors known to affect uptake.
Data shown for separate analyses of () 60–69-year-olds and () 70–74-year-olds.
ⁱAbsolute and relative differences may not exactly equal differences in modelled uptake due to rounding.
ⁱⁱDifferences are not shown for intervention groups that were not statistically significant overall.