Hepatoprotective and Antiviral Efficacy of Acacia mellifera Leaves Fractions against Hepatitis B Virus

Table 2

In vivo effect of A. mellifera (AM) crude ethanolic extract on CCl₄-induced lipid profile changes.

Treatment group	Dose mg/kg	TC (mg/dL)	TG (mg/dL)	HDL-C (mg/dL)	LDL-C (mg/dL)	VLDL-C (mg/dL)
Normal		88.09 ± 6.5	78.26 ± 4.09	50.82 ± 1.25	72.24 ± 6.34	15.56 ± 0.65
CCl4	1.25 mL/kg	212.69 ± 7.84^***a	184.05 ± 8.09^***a	22.14 ± 0.56^***a	175.80 ± 8.42^***a	36.81 ± 1.69^***a
AM + CCl4	250	169.04 ± 11.25^***b	168.59 ± 9.17^b	28.26 ± 1.25^**b	135.22 ± 10.18^*b	33.71 ± 1.83^b
AM + CCl4	500	136.50 ± 4.70^***b	117.37 ± 7.01^***b	36.76 ± 1.02^***b	112.89 ± 4.02^***b	23.47 ± 1.40^***b
Silymarin + CCl4	10	124.60 ± 5.94^***b	98.55 ± 5.60^***b	35.34 ± 1.81^***b	104.74 ± 5.93^***b	19.71 ± 1.12^***b

All values represent mean ± SEM. ^*; ^**; ^***; ANOVA, followed by Dunnett’s multiple comparison test. ^aAs compared with normal group. ^bAs compared with CCl₄ only group.