Research Article

Hepatoprotective and Antiviral Efficacy of Acacia mellifera Leaves Fractions against Hepatitis B Virus

Table 3

Biochemical parameters of rat liver after treatment with A. mellifera (AM) crude ethanolic extract.

Treatment groupDose mg/kgTP (mg/dL)MDA (nmol/g)NP-SH (mg/dL)

Normal95.84 ± 6.270.96 ± 0.118.16 ± 0.42
CCl41.25 mL/kg30.78 ± 3.13***a8.55 ± 1.07***a4.25 ± 0.42***a
AM + CCl425036.21 ± 3.22b5.57 ± 0.77*b6.20 ± 0.56*b
AM + CCl450056.63 ± 3.80***b 2.257 ± 0.20***b6.28 ± 0.48*b
Silymarin + CCl41056.64 ± 7.61***b2.87 ± 0.64***b7.36 ± 0.54**b

All values represent mean ± SEM. *; **; ***; ANOVA, followed by Dunnett’s multiple comparison test. aAs compared with normal group. bAs compared with CCl4 only group.