Sequence and organization of G-patch domains and G-patch protein partners. (a) Sequence alignments of G-patch domains from various G-patch proteins from different organisms. Sequences from G-patch protein partners of DEAH/RHA helicases from human and yeast are in the red box. The consensus sequence of G-patch is written in green: G is a glycine, a represents an aromatic residue, and h represents a hydrophobic residue. G-patch domain is a 50 AA glycine-rich domain with some residues invariably conserved like the aromatic residue after the first glycine. (b) Schematic representation of G-patch protein partners of DEAH/RHA helicases and their domains.