Review Article

Regulation of DEAH/RHA Helicases by G-Patch Proteins

Table 2

Human DEAH/RHA helicases with no known G-patch activator and biological processes in which they are implied. For each protein, the identified yeast ortholog is listed in parenthesis.

DEAH/RHAFunctions

DHX38 (Prp16)Splicing
DHX8 (Prp22)Splicing
DHX37 (Dhr1)Ribosome biogenesis
DHX32 (Dhr2)Ribosome biogenesis
DHX29 (YLR419w)Translation initiation; immunity
DHX33Transcription; immunity
DHX9Genomic stability; immunity; RNA interference
DHX29Translation initiation; immunity
DHX35Splicing
DHX34mRNA decay