Treatment of Endometriosis with the GnRHa Deslorelin and Add-Back Estradiol and Supplementary Testosterone

Table 3

D with add-back had little safety impact on cognition or laboratory parameters and did not cause endometrial hyperplasia. Values are means (SEM) or percentages; indicates a statistically significant difference relative to baseline values, .

	Baseline	3 months	6 months
MOQ total	—	—	—
Concentration	7.6 (0.6)	6.4 (0.6)	6.2 (0.6)
Nonverbal	8.1 (0.3)	7.8 (0.4)	7.5 (0.4)
Prospective	7.8 (0.4)	7.5 (0.5)	7.2 (0.5)
Real world	8.1 (0.4)	8.1 (0.5)	7.3 (0.5)
Superlative	3.2 (0.4)	3.3 (0.4)	2.8 (0.5)
Verbal	7.3 (1.4)	7.0 (0.5)	6.5 (0.5)
Serum lipids	—	—	—
Cholesterol	204.3 (9.4)	—	202.2 (10.0)
HDL	65.2 (2.4)	—	63.6 (3.5)
LDL	121.1 (9.5)	—	115.2 (9.7)
VLDL	18.1 (1.8)	—	23.4 (2.9)
Triglycerides	90.5 (9.2)	—	117.1 (14.6)
	Baseline		6 months
Complete blood count	—	—	—
White blood cells	6.1 (0.4)	—	5.9 (0.4)
Hemoglobin	12.8 (0.2)	—	13.0 (0.2)
Platelets (000)	304 (16.3)	—	275 (16.3)
	Baseline		6 months
Endometrial biopsy	—	—	—
Proliferative	100%	—	100%
Hyperplasia	0%	—	0%
Atrophic	0%	—	0%