BioMed Research International / 2015 / Article / Tab 3

Clinical Study

Zoledronic Acid May Reduce Intraoperative Bleeding in Spinal Tumors: A Prospective Cohort Study

Table 3

Comparison of intraoperative blood loss and surgical approach in 157 patients with metastases.

Intraoperative blood lossPreoperative zoledronic acid group (group A; )Control group (group B; )

Mean ± SD (volume per milliliter)1311 ± 6911752 ± 7400.000
Range (volume per milliliter)380–3400450–4200
Distribution0.001
 ≤500 mL103
 500–1000 mL268
 1001–1500 mL1720
 1501–2000 mL1825
 ≥2001 mL1020
Surgical approach0.704
 Anterior 1214
 Posterior6759
 Combined23