Zoledronic Acid May Reduce Intraoperative Bleeding in Spinal Tumors: A Prospective Cohort Study

Table 4

Comparison of intraoperative blood loss and surgical approach in 19 patients with multiple myeloma.

Intraoperative blood loss	Preoperative zoledronic acid group (group C; )	Control group (group D; )
Mean ± SD (volume per milliliter)	1994 ± 810	3134 ± 795	0.007
Range (volume per milliliter)	890–3200	2200–4450
Distribution			0.041
500–1000 mL	2	0
1001–2000 mL	4	0
2001–3000 mL	3	5
≥3001 mL	1	4
Surgical approach			0.510
Anterior	2	3
Posterior	8	6
Combined	0	0