Mycobacterium-Host Cell Relationships in Granulomatous Lesions in a Mouse Model of Latent Tuberculous Infection

Figure 3

(a) Macrophages (Mph) with different numbers of BCG-mycobacteria (BCG) in the granulomas from mouse 23 S/2 m. Dark bars represent the number of Mph with different BCG numbers calculated as a percentage of the total number of infected Mph in the granulomas. White bars represent the number of Mph containing colonies of replicating BCG-mycobacteria calculated as a percentage of the total number of infected Mph in granulomas. (b) The number of BCG per macrophage in granulomas from different mice calculated as the number of BCG in macrophages relative the total number of infected macrophages (dark bars) or the total number of all granuloma macrophages (white bars) (see text for details). Data are expressed as the means ± SEM. Abbreviations as in the legend to Figure 2. () Leukocyte infiltrates from mouse 6 S/2 m.

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