Table 2: Heart remodeling and hemodynamics at 9 months.

ParametersSham ()AR () value

Ind heart, mg/mm21.3 ± 2.740.1 ± 1.6<0.0001
SAP, mm Hg120 ± 4.0120 ± 3.30.84
DAP, mm Hg90 ± 4.664 ± 2.0<0.0001
PP, mm Hg30 ± 2.156 ± 2.4<0.0001
MAP, mm Hg99 ± 4.383 ± 2.50.007
, mm Hg/sec−5994 ± 327−3871 ± 143<0.0001
, mm Hg/sec7483 ± 3285657 ± 277<0.0001
LVEDP, mm Hg9.6 ± 1.614.4 ± 1.40.044

Measurements obtained under inhaled 1.5% isoflurane anesthesia in surviving animals. Ind heart: indexation was made using tibial length; SAP: systolic arterial pressure; DAP: diastolic arterial pressure; PP: pulse pressure (SAP-DAP); MAP: mean arterial pressure; : minimal derivative of pressure/time; : maximal derivative of pressure/time; LVEDP: left ventricular end-diastolic pressure. Values are mean ± SEM of the indicated number of animals with the exception of and LVEDP values ().