The MicroRNA3686 Inhibits the Proliferation of Pancreas Carcinoma Cell Line by Targeting the Polo-Like Kinase 1

Figure 6

Inhibition of microRNA3686 expression in immortalized human pancreas cell line resulted in enhanced cell proliferation. (a) Cell proliferation assay for mir3686 mimic or scramble control transfected cell indicated time points; each experiment had been conducted for tree times and significant differences between groups are shown by “,” which indicates . (b) The quantification of cell invasion result between scramble control and mir3686 inhibitor transfected HPDE6C7 cell demonstrated that mir3686 inhibition enhance cell invasion. Error bars represent standard errors of three repeated experiments. Significant differences between groups are shown by “,” which indicates ; (c) clonogenic cell survival assay indicated that mir3686 increase the cell colonies formation in mir3686 inhibitor transfected HPDE6C7 cell.

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