Clinical Relevance of Nontuberculous Mycobacteria Isolated from Sputum in a Gold Mining Workforce in South Africa: An Observational, Clinical Study
Table 3
Symptoms reported by route of recruitment to study and species of nontuberculous mycobacterium isolated ().
Species
Number isolated
Number reporting cough (%)
Number reporting night sweats1 (%)
Number reporting haemoptysis (%)
Number reporting weight loss2 (%)
Number reporting fever (%)
Number reporting any symptom (%)
Number with chest radiograph classified as definite or possible active tuberculosis /number with chest radiograph available
Clinic patient group
M. avium complex
25
17 (68)
13 (52)
4 (16)
11 (44)
11 (44)
19 (76)
2/14
M. kansasii
21
11 (52)
9 (43)
1 (5)
10 (48)
9 (43)
14 (67)
4/9
M. parascrofulaceum
9
8 (89)
7 (78)
0
8 (89)
6 (67)
9 (100)
1/7
M. fortuitum
9
7 (78)
5 (56)
0
5 (56)
3 (33)
7 (78)
1/5
M. gordonae
7
5 (71)
2 (29)
0
4 (57)
4 (57)
6 (86)
1/3
New species
7
5 (71)
3 (43)
1 (14)
2 (29)
4 (57)
5 (71)
0/5
Other species
18
13 (72)
11 (61)
3 (17)
7 (39)
10 (56)
15 (83)
1/7
Total
96
66 (69)
50 (52.1)
9 (9.4)
47 (49.0)
47 (49.0)
75 (78.1)
10/50
Pre-IPT3 screening group
M. gordonae
53
26 (49)
12 (23)
§
17 (32)
§
34 (64)
13/46
M. kansasii
29
8 (28)
2 (7.0)
§
6 (21)
§
12 (41)
13/25
M. avium complex
13
8 (62)
5 (39)
§
3 (23)
§
9 (69)
1/12
M. parascrofulaceum
12
2 (17)
2 (17)
§
4 (33)
§
6 (50)
4/11
M. fortuitum
11
5 (46)
3 (27)
§
1 (9)
§
5 (46)
5/10
M. szulgai
5
4 (80)
1 (20)
§
2 (40)
§
4 (80)
2/5
New species
3
1 (33)
1 (33)
§
1 (33)
§
1 (33)
1/2
Other species
10
5 (50)
1 (10)
§
5 (50)
§
6 (60)
1/10
Total
136
59 (43.4)
27 (19.9)
§
39 (28.7)
§
77 (56.6)
40/121
Night sweats were defined by the wording of the question put to study participants: “Do you have drenching night sweats? (Sweat so much at night that clothes/pillows are soaking wet?).” 2Weight loss was defined by the wording of the question put to study participants: “Do you have unintentional weight loss? (In the last 6 months have your clothes become looser?).” 3IPT: isoniazid preventive therapy. Data not available as questionnaire used in pre-IPT screening for tuberculosis did not include this question.
