Research Article

Quantification of Internalized Silica Nanoparticles via STED Microscopy

Table 2

Sedimentation and diffusion simulation results.

Particles/clusterDeposited
134
Particle diameterFraction (%)Particle number (cm−2)Fraction (%)Particle number (cm−2)Fraction (%)Particle number (cm−2)

25 nm26.519.418.3
85 nm20.421.320.8

Results of the ISDD sedimentation model for SNPs with two different diameters (25 and 85 nm) in 1 mL solution with a mass concentration corresponding to 9.2 × 1010 particles mL−1. Simulation results for deposited particles are given as fraction of delivered particles (%) and particle number of deposited particles per cm2. The number of deposited particles displays little dependency on the number of particles per cluster for small cluster sizes and is in the same range for both particle sizes.