Amylose-Based Cationic Star Polymers for siRNA Delivery

Figure 5

Gene silencing effect of nonsense siRNA (siCont)/C1A, sense siRNA (siVEGF)/C1A, siConc/C8A, siVEGF/C8A, SiCont/lipofectamine 2000, and siVEGF/lipofectamine 2000 complexes. [The polymer] = 5 μg; [lipofectamine 2000] = 2 μg. Dose of siRNA for the cationic polymers was 0.3 nM, while dose of siRNA for lipofectamine 2000 was 0.1 nM. C/P ratio was 1.3 for the siRNA/the cationic polymer complexes.