|
| Source | Healthy control | Internal control | Alterative
microRNA | Conclusion |
|
2010
Li et al. [27] | No details | plant miR-168 | miR-25, miR-375,
and let-7f |
Serve as biomarkers for HCC diagnosis |
|
2011
Li et al. [25] | No details | mmu-miR-295 | miR-221 | Provide significance for prognosis of HCC |
|
2011
Gui et al. [26] | No details | U6 snRNAs | miR-885-5p | The detection and assessment of liver pathologies |
|
2011
Xu et al. [23] | Healthy controls were randomly selected from a database consisting of 2500 individuals based on a physical examination | miR-181a
and miR-181c | miR-21, miR-122,
and miR-223 | Serve as biomarkers for liver injury but not specifically for HCC |
|
2011
Qi et al. [24] | No details | miR-16 | miR-122 | Serve as biomarkers for liver injury but not specifically for HCC |
|
2012
Liu et al. [20] | Healthy controls are people who underwent routine physical examinations with no underlying liver diseases | miRNA concentrations were normalised to the total RNA input and expressed as the number of copies per nanogram of RNA | miR-15b and miR-130b | Serve as biomarkers for HCC diagnosis |
|
2012
Li et al. [21] | Volunteers had not been diagnosed with any types of cancer previously based on self-report | U6 snRNAs | miR-18a | Serve as biomarkers for HCC diagnosis |
|
2011
Zhou et al. [22] | No details | miR-1228 | miR-122, miR-192,
miR-21, miR-223,
miR-26a, miR-27a,
and miR-801 | Serve as biomarkers for early-stage HCC diagnosis |
|
2013
Lu et al. [19] | No details | U6 snRNAs | miR-129-2 | Serve as biomarkers for early-stage HCC diagnosis |
|
2013
Wei et al. [18] | No details | U6 snRNAs | miR-132 | miR-132 may be a promising biochemical marker and may have therapeutic applications in HBV-related HCC |
|
2013
Zheng et al. [17] | No details | U6 snRNAs | miR-17-5p | Serve as a noninvasive biomarker for the prognostic prediction of HCC patients. |
|
