TY - JOUR
A2 - Tyan, Yu-Chang
AU - Zhu, Yingzhong
AU - Xiao, Lufei
AU - Zhao, Meng
AU - Zhou, Jiazheng
AU - Zhang, Qiong
AU - Wang, Hui
AU - Li, Shengli
AU - Zhou, Hongping
AU - Wu, Jieying
AU - Tian, Yupeng
PY - 2015
DA - 2015/10/12
TI - A Series of Imidazole Derivatives: Synthesis, Two-Photon Absorption, and Application for Bioimaging
SP - 965386
VL - 2015
AB - A new series of D-π-A type imidazole derivatives have been synthesized and characterized. Two corresponding imidazolium salts (iodine and hexafluorophosphate) were prepared from the imidazole compound. Their electron-withdrawing ability can be largely tunable by salt formation reaction or ion exchange. UV-vis absorption and single-photon fluorescence spectra have been systematically investigated in different solvents. The two-photon cross sections δ2PA of the imidazole derivatives are measured by two-photon excited fluorescence (2PEF) method. Compared with those of T-1 (107 GM) and T-3 (96 GM), T-2 (imidazolium iodine salt) has a large two-photon absorption (2PA) cross section value of 276 GM. Furthermore, the cytotoxicity and applications in bioimaging for the imidazole derivatives were carried out. The results showed that T-1 can be used as a lysosomal tracker with high stability and water solubility within pHs of 4–6, while T-2 and T-3 can be used as probes for cell cytoplasm.
SN - 2314-6133
UR - https://doi.org/10.1155/2015/965386
DO - 10.1155/2015/965386
JF - BioMed Research International
PB - Hindawi Publishing Corporation
KW -
ER -