Epoetin Alpha and Epoetin Zeta: A Comparative Study on Stimulation of Angiogenesis and Wound Repair in an Experimental Model of Burn Injury

Figure 3

Effects of EPO-α and EPO-Z on VEGF (a) protein expression in skin tissue samples. EPO-α increases the expression of VEGF at all time points even if not significantly. The administration of EPO-Z significantly increases the expression of VEGF at both 3 and 12 days. versus untreated; versus untreated. Effects of EPO-α and EPO-Z treatment on cyclin D1 (b) and CDK6 (c) proteins expression in skin tissue samples. versus untreated and EPO-Z, versus untreated and EPO-Z. Values are expressed as mean and SD for each group. Significance between treatments is considered within the same day of observation.

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