Exposure to Allergen Causes Changes in NTS Neural Activities after Intratracheal Capsaicin Application, in Endocannabinoid Levels and in the Glia Morphology of NTS

<div>Effect of vehicle (20% DMSO in ACSF) or capsaicin (300 pg in 20 <i>μ</i>L) in naïve (a) and sensitized (b) rats. L-AP4 (4 nmol/rat) (hollow arrow) prevented the capsaicin (full arrow) induced increase in the airway-related NTS neuron ongoing activities. This effect of L-AP4 (4 nmol/rat) was prevented by pretreatment with MSOP (100 nmol/rat) (arrow with lines). 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Values statistically (<svg height="9.04777pt" id="M19" style="vertical-align:-0.04981995pt" version="1.1" viewbox="-0.0498162 -8.99795 8.4902 9.04777" width="8.4902pt" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink"><g transform="matrix(.0135,0,0,-0.0135,0,0)"><path d="M600 480C600 590 528 650 384 650H143L137 622C222 614 225 607 210 531L130 127C113 41 106 36 23 28L17 0H294L300 28C204 36 195 42 212 127L243 284L314 263C327 263 339 263 352 264C465 271 600 337 600 480ZM508 481C508 351 402 304 329 304C289 304 265 311 250 317L295 559C302 594 310 606 323 611C335 616 350 619 367 619C455 619 508 573 508 481Z" id="g113-81"></path><glyph.data ascent="3473" descent="-2876" horiz-adv-x="617" vert-adv-y="617"></glyph.data></g></svg> value &lt; 0.05) significant versus the respective control were indicated as open symbols.</div>

BioMed Research International

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Figure 3

Figure 3: Exposure to Allergen Causes Changes in NTS Neural Activities after Intratracheal Capsaicin Application, in Endocannabinoid Levels and in the Glia Morphology of NTS 

Figure 3 | Exposure to Allergen Causes Changes in NTS Neural Activities after Intratracheal Capsaicin Application, in Endocannabinoid Levels and in the Glia Morphology of NTS 