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BioMed Research International
Volume 2015 (2015), Article ID 981471, 5 pages
Research Article

Relationship between Outer Retinal Layers Thickness and Visual Acuity in Diabetic Macular Edema

1Department of Ophthalmology, The University of Hong Kong, Room 301, Level 3, Block B, Cyberport 4, Pokfulam, Hong Kong
2Department of Ophthalmology and Visual Science, The Chinese University of Hong Kong, Kowloon, Hong Kong
3Department of Ophthalmology, Caritas Medical Centre, Kowloon, Hong Kong

Received 10 September 2014; Accepted 23 March 2015

Academic Editor: Paolo Frezzotti

Copyright © 2015 Raymond L. M. Wong et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Purpose. To investigate the correlation of outer retinal layers (ORL) thickness and visual acuity (VA) in patients with diabetic macular edema (DME). Methods. Consecutive DME patients seen at the Retina Clinic of The University of Hong Kong were recruited for OCT assessment. The ORL thickness was defined as the distance between external limiting membrane (ELM) and retinal pigment epithelium (RPE) at the foveal center. The correlation between total retinal thickness, ORL thickness, and vision was calculated. Results. 78 patients with DME were recruited. The mean age was 58.1 years (±11.5 years) and their mean visual acuity measured with Snellen chart was 0.51 (±0.18). The correlation coefficient between total retinal thickness and visual acuity was 0.34 (P < 0.001) whereas the correlation coefficient was 0.65 between ORL thickness and visual acuity (P < 0.001). Conclusion. ORL thickness correlates better with vision than the total retinal thickness. It is a novel OCT parameter in the assessment of DME. Moreover, it could be a potential long term visual prognostic factor for patients with DME.