Translationally Controlled Tumor Protein in Prostatic Adenocarcinoma: Correlation with Tumor Grading and Treatment-Related Changes
Table 1
Main characteristics of the patients included in this study. Univariate descriptive statistics (including frequencies and percentages) of each qualitative clinical parameter in relation to the two TCTP protein expression levels is shown with the relative value. A statistically significant association between TCTP protein expression and the main prognostic factors involved in PC aggressiveness is detected.
Variable
Group
TCTP protein expression
value
High
Low
Preoperative PSA
<4
6 (2%)
1 (0.8%)
5 (3.1%)
<0.05
4–10
95 (32.5%)
27 (20.6%)
68 (42.2%)
>10
191 (65.5%)
103 (78.6%)
88 (54.7%)
Surgical margins infiltration
Present
162 (55.5%)
91 (69.5%)
71 (44.1%)
<0.001
Absent
130 (44.5%)
40 (30.5%)
90 (55.9%)
Extraprostatic extension
Present
129 (44.2%)
91 (69.5%)
38 (23.6%)
<0.001
Absent
163 (55.8%)
40 (30.5%)
123 (76.4%)
Seminal vesicles invasion
Present
49 (16.8%)
40 (30.5%)
9 (5.6%)
<0.001
Absent
243 (83.2%)
91 (69.5%)
152 (94.4%)
Lymph node metastasis
Present
34 (11.6%)
33 (25.2%)
1 (0.6%)
<0.001
Absent
258 (88.4%)
98 (74.8%)
160 (99.4%)
TNM stage
I
29 (9.9%)
0 (0%)
29 (18%)
<0.001
II
128 (43.9%)
37 (28.2%)
91 (56.5%)
III
102 (34.9%)
62 (47.4%)
40 (24.9%)
IV
33 (11.3%)
32 (24.4%)
1 (0.6%)
Recurrence
Present
120 (41.4%)
114 (87%)
6 (3.7%)
<0.001
Absent
172 (58.6%)
17 (13%)
155 (96.3%)
PC: prostatic cancer; : number of cases and percentage.
