A Polyethylenimine-Containing and Transferrin-Conjugated Lipid Nanoparticle System for Antisense Oligonucleotide Delivery to AML

<div>Serum stability. The electrophoresis bands in the figure represent retained intact G3139 in serum after incubation. (a) Release of G3139 from Tf-LPN-G3139 by SDS in the absence of serum. (b) Time course of Tf-LPN-G3139 incubation in serum. (c) Tf-LPN-G3139 and control formulations after 4-hour incubation in serum.</div>

BioMed Research International

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Figure 2

Figure 2: A Polyethylenimine-Containing and Transferrin-Conjugated Lipid Nanoparticle System for Antisense Oligonucleotide Delivery to AML 