Interactions between CYP11B2 Promoter Methylation and Smoking Increase Risk of Essential Hypertension

Table 1

Baseline characteristics of the study participants ().

Characteristic	EH	Non-EH
Age (years)			0.324	0.747
Gender	38/58	38/58	0	1.000
ALP (IU/I)			3.125	0.002
GGT (U/L)			−2.796	0.006
BUN (mmol/L)			−0.455	0.650
Scr (μmol/L)			−0.463	0.644
BUA (μmol/L)			−2.258	0.025
TG (mmol/L)			−2.165	0.032
HDL (mmol/L)			6.890	<0.001
LDL (mmol/L)			0.924	0.357
Hcy (μmol/L)			−1.286	0.200
BMI (kg/m^2)			−3.580	<0.001
Smoking (Y/N)		17/79	2.948	0.086
Drinking (Y/N)		31/65	1.810	0.178
CpG1 methylation (%)			0.653
CpG2 methylation (%)			1.039
CpG3 methylation (%)			1.606
CpG4 methylation (%)			0.374

was adjusted by logistic regression for age, gender, BUA, smoking, drinking, BMI, TG, HDL, LDL, and Hcy. BMI: body mass index; ALP: alkaline phosphatase; TG: triglycerides; HDL: high-density lipoprotein; LDL: low-density lipoprotein; Hcy: homocysteine.