Table of Contents Author Guidelines Submit a Manuscript
BioMed Research International
Volume 2016, Article ID 1538703, 11 pages
http://dx.doi.org/10.1155/2016/1538703
Research Article

Biological Activities of Aerial Parts Extracts of Euphorbia characias

1Department of Public Health, Clinical and Molecular Medicine, University of Cagliari, Cittadella Universitaria, 09042 Monserrato, Italy
2Department of Sciences of Life and Environment, University of Cagliari, Cittadella Universitaria, 09042 Monserrato, Italy
3Department of Pharmacy, University of Salerno, 84084 Fisciano, Italy

Received 22 January 2016; Revised 27 April 2016; Accepted 3 May 2016

Academic Editor: Ibrahim M. Banat

Copyright © 2016 Maria Barbara Pisano et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. M. García-Alonso, S. De Pascual-Teresa, C. Santos-Buelga, and J. C. Rivas-Gonzalo, “Evaluation of the antioxidant properties of fruits,” Food Chemistry, vol. 84, no. 1, pp. 13–18, 2004. View at Publisher · View at Google Scholar · View at Scopus
  2. S. Kumar and A. K. Pandey, “Chemistry and biological activities of flavonoids: an overview,” The Scientific World Journal, vol. 2013, Article ID 162750, 16 pages, 2013. View at Publisher · View at Google Scholar · View at Scopus
  3. Y. Xie, W. Yang, X. Chen, and J. Xiao, “Inhibition of flavonoids on acetylcholine esterase: binding and structure–activity relationship,” Food & Function, vol. 5, no. 10, pp. 2582–2589, 2014. View at Publisher · View at Google Scholar · View at Scopus
  4. S. Cosentino, C. I. G. Tuberoso, B. Pisano et al., “In-vitro antimicrobial activity and chemical composition of Sardinian Thymus essential oils,” Letters in Applied Microbiology, vol. 29, no. 2, pp. 130–135, 1999. View at Publisher · View at Google Scholar · View at Scopus
  5. S. Cosentino, A. Barra, B. Pisano, M. Cabizza, F. M. Pirisi, and F. Palmas, “Composition and antimicrobial properties of Sardinian Juniperus essential oils against foodborne pathogens and spoilage microorganisms,” Journal of Food Protection, vol. 66, no. 7, pp. 1288–1291, 2003. View at Google Scholar · View at Scopus
  6. A. Upadhyay, I. Upadhyaya, A. Kollanoor-Johny, and K. Venkitanarayanan, “Combating pathogenic microorganisms using plant-derived antimicrobials: a minireview of the mechanistic basis,” BioMed Research International, vol. 2014, Article ID 761741, 18 pages, 2014. View at Publisher · View at Google Scholar · View at Scopus
  7. F. Esposito, L. Zinzula, A. Maxia, E. Tramontano, and C. Sanna, “Inhibition of HIV-1 reverse transcriptase associated activities by the hydroalcoholic extract of Casimiroa edulis seeds,” Natural Product Research, vol. 25, no. 11, pp. 1067–1073, 2011. View at Publisher · View at Google Scholar · View at Scopus
  8. F. Esposito, C. Sanna, C. Del Vecchio et al., “Hypericum hircinum L. components as new single-molecule inhibitors of both HIV-1 reverse transcriptase-associated DNA polymerase and ribonuclease H activities,” Pathogens and Disease, vol. 68, no. 3, pp. 116–124, 2013. View at Publisher · View at Google Scholar · View at Scopus
  9. B.-S. Min, N. Nakamura, H. Miyashiro, Y.-H. Kim, and M. Hattori, “Inhibition of human immunodeficiency virus type 1 reverse transcriptase and ribonuclease H activities by constituents of Juglans mandshurica,” Chemical & Pharmaceutical Bulletin, vol. 48, no. 2, pp. 194–200, 2000. View at Publisher · View at Google Scholar · View at Scopus
  10. L. Xu, N. Grandi, C. Del Vecchio et al., “From the traditional Chinese medicine plant Schisandra chinensis new scaffolds effective on HIV-1 reverse transcriptase resistant to non-nucleoside inhibitors,” Journal of Microbiology, vol. 53, no. 4, pp. 288–293, 2015. View at Publisher · View at Google Scholar · View at Scopus
  11. J. T. Mwine and P. Van Damme, “Why do Euphorbiaceae tick as medicinal plants? A review of Euphorbiaceae family and its medicinal features,” Journal of Medicinal Plants Research, vol. 5, no. 5, pp. 652–662, 2011. View at Google Scholar · View at Scopus
  12. Q.-W. Shi, X.-H. Su, and H. Kiyota, “Chemical and pharmacological research of the plants in genus Euphorbia,” Chemical Reviews, vol. 108, no. 10, pp. 4295–4327, 2008. View at Publisher · View at Google Scholar · View at Scopus
  13. D. Spanò, F. Pintus, C. Mascia et al., “Extraction and characterization of a natural rubber from Euphorbia characias latex,” Biopolymers, vol. 97, no. 8, pp. 589–594, 2012. View at Publisher · View at Google Scholar · View at Scopus
  14. D. Spanò, F. Pintus, F. Esposito, D. Loche, G. Floris, and R. Medda, “Euphorbia characias latex: micromorphology of rubber particles and rubber transferase activity,” Plant Physiology and Biochemistry, vol. 87, pp. 26–34, 2015. View at Publisher · View at Google Scholar · View at Scopus
  15. E. Dainese, A. Sabatucci, F. Pintus et al., “Domain mobility as probed by small-angle X-ray scattering may account for substrate access to the active site of two copper-dependent amine oxidases,” Acta Crystallographica Section D: Biological Crystallography, vol. 70, no. 8, pp. 2101–2110, 2014. View at Publisher · View at Google Scholar · View at Scopus
  16. F. Pintus, D. Spanò, A. Bellelli, F. Angelucci, G. Floris, and R. Medda, “Nucleotide pyrophosphatase/phosphodiesterase from Euphorbia characias latex: purification and characterization,” Plant Science, vol. 177, no. 6, pp. 636–642, 2009. View at Publisher · View at Google Scholar · View at Scopus
  17. F. Pintus, D. Spanò, A. Bellelli et al., “Euphorbia peroxidase catalyzes thiocyanate oxidation in two different ways, the distal calcium ion playing an essential role,” Biochemistry, vol. 49, no. 40, pp. 8739–8747, 2010. View at Publisher · View at Google Scholar · View at Scopus
  18. F. Pintus, R. Medda, A. C. Rinaldi, D. Spanò, and G. Floris, “Euphorbia latex biochemistry: complex interactions in a complex environment,” Plant Biosystems, vol. 144, no. 2, pp. 381–391, 2010. View at Publisher · View at Google Scholar · View at Scopus
  19. F. Pintus, D. Spano, S. Corongiu, G. Floris, and R. Medda, “Purification, primary structure, and properties of Euphorbia characias latex purple acid phosphatase,” Biochemistry, vol. 76, no. 6, pp. 694–701, 2011. View at Publisher · View at Google Scholar · View at Scopus
  20. D. Spanò, K. Pospiskova, I. Safarik et al., “Chitinase III in Euphorbia characias latex: purification and characterization,” Protein Expression and Purification, vol. 116, pp. 152–158, 2015. View at Publisher · View at Google Scholar · View at Scopus
  21. A. Mura, F. Pintus, A. Fais et al., “Tyramine oxidation by copper/TPQ amine oxidase and peroxidase from Euphorbia characias latex,” Archives of Biochemistry and Biophysics, vol. 475, no. 1, pp. 18–24, 2008. View at Publisher · View at Google Scholar · View at Scopus
  22. F. Pintus, D. Spanò, G. Floris, and R. Medda, “Euphorbia characias latex amine oxidase and peroxidase: interacting enzymes?” Protein Journal, vol. 32, no. 6, pp. 435–441, 2013. View at Publisher · View at Google Scholar · View at Scopus
  23. M. Palomino-Schätzlein, P. V. Escrig, H. Boira, J. Primo, A. Pineda-Lucena, and N. Cabedo, “Evaluation of nonpolar metabolites in plant extracts by 13C NMR spectroscopy,” Journal of Agricultural and Food Chemistry, vol. 59, no. 21, pp. 11407–11416, 2011. View at Publisher · View at Google Scholar · View at Scopus
  24. F. Pintus, D. Spanò, A. Corona, and R. Medda, “Antityrosinase activity of Euphorbia characias extracts,” PeerJ, vol. 3, article e1305, 2015. View at Publisher · View at Google Scholar
  25. P. V. Escrig, D. J. Iglesias, A. Corma, J. Primo, E. Primo-Millo, and N. Cabedo, “Euphorbia characias as bioenergy crop: a study of variations in energy value components according to phenology and water status,” Journal of Agricultural and Food Chemistry, vol. 61, no. 42, pp. 10096–10109, 2013. View at Publisher · View at Google Scholar · View at Scopus
  26. A. Corona, T. Masaoka, G. Tocco, E. Tramontano, and S. F. J. Le Grice, “Active site and allosteric inhibitors of the ribonuclease H activity of HIV reverse transcriptase,” Future Medicinal Chemistry, vol. 5, no. 18, pp. 2127–2139, 2013. View at Publisher · View at Google Scholar · View at Scopus
  27. F. Esposito, A. Corona, and E. Tramontano, “HIV-1 reverse transcriptase still remains a new drug target: structure, function, classical inhibitors, and new inhibitors with innovative mechanisms of actions,” Molecular Biology International, vol. 2012, Article ID 586401, 23 pages, 2012. View at Publisher · View at Google Scholar
  28. R. Re, N. Pellegrini, A. Proteggente, A. Pannala, M. Yang, and C. Rice-Evans, “Antioxidant activity applying an improved ABTS radical cation decolorization assay,” Free Radical Biology and Medicine, vol. 26, no. 9-10, pp. 1231–1237, 1999. View at Publisher · View at Google Scholar · View at Scopus
  29. F. Pintus, D. Spanò, C. Mascia, A. Macone, G. Floris, and R. Medda, “Acetylcholinesterase inhibitory and antioxidant properties of Euphorbia characias latex,” Records of Natural Products, vol. 7, no. 2, pp. 147–151, 2013. View at Google Scholar · View at Scopus
  30. C. I. G. Tuberoso, M. Boban, E. Bifulco, D. Budimir, and F. M. Pirisi, “Antioxidant capacity and vasodilatory properties of Mediterranean food: the case of Cannonau wine, myrtle berries liqueur and strawberry-tree honey,” Food Chemistry, vol. 140, no. 4, pp. 686–691, 2013. View at Publisher · View at Google Scholar · View at Scopus
  31. G. L. Delogu, M. J. Matos, M. Fanti et al., “2-Phenylbenzofuran derivatives as butyrylcholinesterase inhibitors: synthesis, biological activity and molecular modeling,” Bioorganic & Medicinal Chemistry Letters, vol. 26, no. 9, pp. 2308–2313, 2016. View at Publisher · View at Google Scholar
  32. F. Esposito, A. Corona, L. Zinzula, T. Kharlamova, and E. Tramontano, “New anthraquinone derivatives as inhibitors of the HIV-1 reverse transcriptase-associated ribonuclease H function,” Chemotherapy, vol. 58, no. 4, pp. 299–307, 2012. View at Publisher · View at Google Scholar · View at Scopus
  33. A. Corona, F. S. Di Leva, S. Thierry et al., “Identification of highly conserved residues involved in inhibition of HIV-1 RNase H function by diketo acid derivatives,” Antimicrobial Agents and Chemotherapy, vol. 58, no. 10, pp. 6101–6110, 2014. View at Publisher · View at Google Scholar · View at Scopus
  34. A. Corona, A. Schneider, K. Schweimer, P. Rösch, B. M. Wöhrl, and E. Tramontano, “Inhibition of foamy virus reverse transcriptase by human immunodeficiency virus type 1 RNase H inhibitors,” Antimicrobial Agents and Chemotherapy, vol. 58, no. 7, pp. 4086–4093, 2014. View at Publisher · View at Google Scholar · View at Scopus
  35. H. Horai, M. Arita, S. Kanaya et al., “MassBank: a public repository for sharing mass spectral data for life sciences,” Journal of Mass Spectrometry, vol. 45, no. 7, pp. 703–714, 2010. View at Publisher · View at Google Scholar · View at Scopus
  36. P. Hou, Y. Zeng, B. Ma et al., “A fast, sensitive, and high-throughput method for the simultaneous quantitation of three ellagitannins from Euphorbiae pekinensis Radix in rat plasma by ultra-HPLC-MS/MS,” Journal of Separation Science, vol. 36, no. 15, pp. 2544–2551, 2013. View at Publisher · View at Google Scholar · View at Scopus
  37. R. A. Dixon and G. M. Pasinetti, “Flavonoids and isoflavonoids: from plant biology to agriculture and neuroscience,” Plant Physiology, vol. 154, no. 2, pp. 453–457, 2010. View at Publisher · View at Google Scholar · View at Scopus
  38. P. J. Houghton, Y. Ren, and M.-J. Howes, “Acetylcholinesterase inhibitors from plants and fungi,” Natural Product Reports, vol. 23, no. 2, pp. 181–199, 2006. View at Publisher · View at Google Scholar · View at Scopus
  39. J. Lin, J. Dou, J. Xu, and H. A. Aisa, “Chemical composition, antimicrobial and antitumor activities of the essential oils and crude extracts of Euphorbia macrorrhiza,” Molecules, vol. 17, no. 5, pp. 5030–5039, 2012. View at Publisher · View at Google Scholar · View at Scopus
  40. S. Perumal, R. Mahmud, S. Pillai, W. C. Lee, and S. Ramanathan, “Antimicrobial activity and cytotoxicity evaluation of Euphorbia hirta (L.) extracts from Malaysia,” APCBEE Procedia, vol. 2, pp. 80–85, 2012. View at Publisher · View at Google Scholar
  41. Y. Deng, G. Yang, J. Yue et al., “Influences of ripening stages and extracting solvents on the polyphenolic compounds, antimicrobial and antioxidant activities of blueberry leaf extracts,” Food Control, vol. 38, no. 1, pp. 184–191, 2014. View at Publisher · View at Google Scholar · View at Scopus
  42. H. Ikigai, T. Nakae, Y. Hara, and T. Shimamura, “Bactericidal catechins damage the lipid bilayer,” Biochimica et Biophysica Acta (BBA)—Biomembranes, vol. 1147, no. 1, pp. 132–136, 1993. View at Publisher · View at Google Scholar · View at Scopus
  43. A. M. Janssen, J. J. C. Scheffer, and A. Baerheim Svendsen, “Antimicrobial activity of essential oils: a 1976–1986 literature review. Aspects of the test methods,” Planta Medica, vol. 53, no. 5, pp. 395–398, 1987. View at Publisher · View at Google Scholar · View at Scopus
  44. T. Kulisic-Bilusic, V. Katalinic, V. Dragovic-Uzelac et al., “Antioxidant and AChE inhibiting activity of tea,” Food Technology and Biotechnology, vol. 46, pp. 368–375, 2008. View at Google Scholar
  45. N. Suganthy and K. Pandima Devi, “In vitro antioxidant and anti-cholinesterase activities of Rhizophora mucronata,” Pharmaceutical Biology, vol. 54, no. 1, pp. 118–129, 2016. View at Publisher · View at Google Scholar
  46. M. A. Aderogba, A. R. Ndhlala, K. R. R. Rengasamy, and J. Van Staden, “Antimicrobial and selected in vitro enzyme inhibitory effects of leaf extracts, flavonols and indole alkaloids isolated from Croton menyharthii,” Molecules, vol. 18, no. 10, pp. 12633–12644, 2013. View at Publisher · View at Google Scholar · View at Scopus
  47. S. Pasetto, V. Pardi, and R. M. Murata, “Anti-HIV-1 activity of flavonoid myricetin on HIV-1 infection in a dual-chamber in vitro model,” PLoS ONE, vol. 9, no. 12, Article ID e115323, 18 pages, 2014. View at Publisher · View at Google Scholar · View at Scopus
  48. M. M. Senthamilselvi, D. Kesavan, and N. Sulochana, “An anti-inflammatory and anti-microbial flavone glycoside from flowers of Cleome viscosa,” Organic and Medicinal Chemistry Letters, vol. 2, article 19, pp. 1–5, 2012. View at Publisher · View at Google Scholar