Research Article

Biological Activities of Aerial Parts Extracts of Euphorbia characias

Table 4

Effects of E. characias extracts on HIV-1 RT-associated functions.

ExtractsIC50 (g/mL)
HIV-1HIV-1
RDDP RNase H

LeavesAqueous0.785 ± 0.0031.95 ± 1.03
Ethanolic0.75 ± 0.0280.685 ± 0.155

StemsAqueous6.87 ± 0.812.235 ± 0.245
Ethanolic3.05 ± 0.21.615 ± 0.035

FlowersAqueous1.03 ± 0.01.51 ± 0.53
Ethanolic0.26 ± 0.080.33 ± 0.1

Efavirenz0.0016 ± 0.0003ND

RDS1759ND7.1 ± 0.5

Extracts concentration required to inhibit HIV-1 RT-associated functions by 50%.
Values expressed in M concentration.
Not done.
Means followed by distinct letters in the same column are significantly different ().