Research Article
Circular RNA-ITCH Suppresses Lung Cancer Proliferation via Inhibiting the Wnt/β-Catenin Pathway
Table 1
Baseline demographic and clinical characteristics of study populations.
| Characteristics | Population | cir-ITCH relative expression | value | | (%) |
| Age (years) | | | | | ≤40 | 10 | 12.82 | 0.0607 ± 0.0169 | 0.0076 | 40–60 | 31 | 39.74 | 0.0466 ± 0.0307 | ≥60 | 37 | 47.44 | 0.0357 ± 0.0155 |
| Sex | | | | | Male | 45 | 57.7 | 0.0432 ± 0.0257 | 0.9704 | Female | 33 | 42.3 | 0.0434 ± 0.0225 |
| Family history | | | | | Yes | 23 | 29.49 | 0.0441 ± 0.0290 | 0.8437 | No | 55 | 70.51 | 0.0429 ± 0.0221 |
| Smoking | | | | | Never | 53 | 67.95 | 0.0487 ± 0.0283 | 0.1713 | Ever | 25 | 32.05 | 0.0407 ± 0.0230 |
| Drinking | | | | | Never | 33 | 42.3 | 0.0478 ± 0.2352 | 0.1568 | Ever | 45 | 57.7 | 0.0399 ± 0.0244 |
| Tumor type | | | | | Adenocarcinoma | 29 | 37.18 | 0.0443 ± 0.0267 | 0.9183 | Large cell carcinoma | 25 | 32.05 | 0.0436 ± 0.0250 | Squamous cell carcinoma | 24 | 30.77 | 0.0416 ± 0.0218 |
| Stage | | | | | I | 18 | 23.08 | 0.0605 ± 0.0273 | 0.0011 | II | 21 | 26.92 | 0.0444 ± 0.0260 | III | 22 | 28.21 | 0.0375 ± 0.0182 | IV | 17 | 21.79 | 0.0309 ± 0.0142 |
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< 0.05 means statistically significant difference existed within subgroups. Relative expression value was normalized to GAPDH expression level.
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