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BioMed Research International
Volume 2016, Article ID 1614328, 6 pages
http://dx.doi.org/10.1155/2016/1614328
Review Article

Spinal Epidural Abscess: A Review with Special Emphasis on Earlier Diagnosis

Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA

Received 14 July 2016; Accepted 24 October 2016

Academic Editor: André Talvani

Copyright © 2016 Allison Bond and Farrin A. Manian. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. D. P. Davis, A. Salazar, T. C. Chan, and G. M. Vilke, “Prospective evaluation of a clinical decision guideline to diagnose spinal epidural abscess in patients who present to the emergency department with spine pain,” Journal of Neurosurgery: Spine, vol. 14, no. 6, pp. 765–770, 2011. View at Publisher · View at Google Scholar · View at Scopus
  2. E. S. Nussbaum, D. Rigamonti, H. Standiford, Y. Numaguchi, A. L. Wolf, and W. L. Robinson, “Spinal epidural abscess: a report of 40 cases and review,” Surgical Neurology, vol. 38, no. 3, pp. 225–231, 1992. View at Publisher · View at Google Scholar · View at Scopus
  3. P. Sendi, T. Bregenzer, and W. Zimmerli, “Spinal epidural abscess in clinical practice,” Quarterly Journal of Medicine, vol. 101, no. 1, pp. 1–12, 2008. View at Publisher · View at Google Scholar · View at Scopus
  4. K. Kan and M. Mehta, Microbiology for Surgical Infections: Diagnosis, Prognosis and Treatment, Spinal Epidural Abscesses, 2014.
  5. M. Shousha and H. Boehm, “Surgical treatment of cervical spondylodiscitis: a review of 30 consecutive patients,” Spine, vol. 37, no. 1, pp. E30–E36, 2012. View at Publisher · View at Google Scholar · View at Scopus
  6. I. Strauss, N. Carmi-Oren, A. Hassner et al., “Spinal epidural abscess: in search of reasons for increased incidence,” The Israel Medical Association Journal, vol. 15, no. 9, pp. 560–564, 2013. View at Google Scholar
  7. E. Reihsaus, H. Waldbaur, and W. Seeling, “Spinal epidural abscess: a meta-analysis of 915 patients,” Neurosurgical Review, vol. 23, no. 4, pp. 175–204, 2000. View at Publisher · View at Google Scholar · View at Scopus
  8. R. O. Darouiche, “Spinal epidural abscess,” New England Journal of Medicine, vol. 355, no. 19, pp. 2012–2020, 2006. View at Publisher · View at Google Scholar · View at Scopus
  9. G. Pradilla, G. P. Ardila, W. Hsu, and D. Rigamonti, “Epidural abscesses of the CNS,” The Lancet Neurology, vol. 8, no. 3, pp. 292–300, 2009. View at Publisher · View at Google Scholar · View at Scopus
  10. W. Y. Cheung and K. D. K. Luk, “Pyogenic spondylitis,” International Orthopaedics, vol. 36, no. 2, pp. 397–404, 2012. View at Publisher · View at Google Scholar · View at Scopus
  11. R. M. Duarte and A. R. Vaccaro, “Spinal infection: State of the art and management algorithm,” European Spine Journal, vol. 22, no. 12, pp. 2787–2799, 2013. View at Publisher · View at Google Scholar · View at Scopus
  12. N. H. Shah and K. L. Roos, “Spinal epidural abscess and paralytic mechanisms,” Current Opinion in Neurology, vol. 26, no. 3, pp. 314–317, 2013. View at Publisher · View at Google Scholar · View at Scopus
  13. K. Rosc-Bereza, M. Arkuszewski, E. Ciach-Wysocka, and M. Boczarska-Jedynak, “Spinal epidural abscess: common symptoms of an emergency condition,” Neuroradiology Journal, vol. 26, no. 4, pp. 464–468, 2013. View at Publisher · View at Google Scholar · View at Scopus
  14. P. Krishnamohan and J. R. Berger, “Spinal epidural abscess,” Current Infectious Disease Reports, vol. 16, no. 11, p. 436, 2014. View at Publisher · View at Google Scholar
  15. M. Tompkins, I. Panuncialman, P. Lucas, and M. Palumbo, “Spinal epidural abscess,” Journal of Emergency Medicine, vol. 39, no. 3, pp. 384–390, 2010. View at Publisher · View at Google Scholar · View at Scopus
  16. M. Kundi, “Causality and the interpretation of epidemiologic evidence,” Environmental Health Perspectives, vol. 114, no. 7, pp. 969–974, 2006. View at Publisher · View at Google Scholar · View at Scopus
  17. J. D. Beck, “Risk revisited,” Community Dentistry and Oral Epidemiology, vol. 26, no. 4, pp. 220–225, 1998. View at Publisher · View at Google Scholar · View at Scopus
  18. H. C. Kraemer, A. E. Kazdin, D. R. Offord, R. C. Kessler, P. S. Jensen, and D. J. Kupfer, “Coming to terms with the terms of risk,” Archives of General Psychiatry, vol. 54, no. 4, pp. 337–343, 1997. View at Publisher · View at Google Scholar · View at Scopus
  19. Y. Erşahin, “Spinal epidural abscess: a meta-analysis of 915 patients,” Neurosurgical Review, vol. 24, no. 2-3, p. 156, 2001. View at Publisher · View at Google Scholar · View at Scopus
  20. K. Middleton and D. E. Fish, “Lumbar spondylosis: clinical presentation and treatment approaches,” Current Reviews in Musculoskeletal Medicine, vol. 2, no. 2, pp. 94–104, 2009. View at Publisher · View at Google Scholar · View at Scopus
  21. M. F. Lin, Y. J. Lau, B. S. Hu, Z. Y. Shi, and Y. H. Lin, “Pyogenic psoas abscess: analysis of 27 cases,” Journal of microbiology, immunology, and infection, vol. 32, no. 4, pp. 261–268, 1999. View at Google Scholar · View at Scopus
  22. S. Kastenbauer, H.-W. Pfister, and W. M. Scheld, “Epidural abscess,” in Infections of the Central Nervous System, W. M. Schedl, R. J. Whitely, and C. M. Marra, Eds., pp. 509–522, Lippincott Williams & Wilkins, Philadelphia, Pa, USA, 2004. View at Google Scholar
  23. R. D. Zafonte, J. H. Ricker, R. A. Hanks, D. L. Wood, A. Amin, and L. Lombard, “Spinal epidural abscess: study of early outcome,” Journal of Spinal Cord Medicine, vol. 26, no. 4, pp. 345–351, 2003. View at Publisher · View at Google Scholar · View at Scopus
  24. M. Angsuwat, B. Kavar, and A. J. Lowe, “Early detection of spinal sepsis,” Journal of Clinical Neuroscience, vol. 17, no. 1, pp. 59–63, 2010. View at Publisher · View at Google Scholar · View at Scopus
  25. K. B. Laupland, D. L. Church, M. Mucenski, L. R. Sutherland, and H. D. Davies, “Population-based study of the epidemiology of and the risk factors for invasive Staphylococcus aureus infections,” Journal of Infectious Diseases, vol. 187, no. 9, pp. 1452–1459, 2003. View at Publisher · View at Google Scholar · View at Scopus
  26. C. Hernandez, N. Cobos-Trigueros, C. Feher et al., “Community-onset bacteraemia of unknown origin: clinical characteristics, epidemiology and outcome,” European Journal of Clinical Microbiology and Infectious Diseases, vol. 33, no. 11, pp. 1973–1980, 2014. View at Publisher · View at Google Scholar · View at Scopus
  27. A. R. Patel, T. B. Alton, R. J. Bransford, M. J. Lee, C. B. Bellabarba, and J. R. Chapman, “Spinal epidural abscesses: risk factors, medical versus surgical management, a retrospective review of 128 cases,” Spine Journal, vol. 14, no. 2, pp. 326–330, 2014. View at Publisher · View at Google Scholar · View at Scopus
  28. P. Sørensen, “Spinal epidural abscesses: conservative treatment for selected subgroups of patients,” British Journal of Neurosurgery, vol. 17, no. 6, pp. 513–518, 2003. View at Publisher · View at Google Scholar · View at Scopus
  29. M. Soehle and T. Wallenfang, “Spinal epidural abscesses: clinical manifestations, prognostic factors, and outcomes,” Neurosurgery, vol. 51, no. 1, pp. 79–87, 2002. View at Publisher · View at Google Scholar · View at Scopus
  30. S. M. Patel, J. H. Mo, M. T. Walker, B. Adley, and G. A. Noskin, “Epidural abscess and osteomyelitis due to Actinobacillus actinomycetemcomitans,” Diagnostic Microbiology and Infectious Disease, vol. 50, no. 4, pp. 283–285, 2004. View at Publisher · View at Google Scholar · View at Scopus
  31. S. Korfias, G. A. Alexiou, E. Vlachakis, and D. E. Sakas, “Cervical epidural abscess of odontogenic origin,” Neurological Sciences, vol. 36, no. 6, pp. 1017–1018, 2015. View at Publisher · View at Google Scholar · View at Scopus
  32. S. I. Goolamali, M. T. Carulli, and U. M. Davies, “Spinal abscess and mitral valve endocarditis secondary to asymptomatic fusobacterium-induced dental abscess,” Journal of the Royal Society of Medicine, vol. 99, no. 7, pp. 368–369, 2006. View at Publisher · View at Google Scholar · View at Scopus
  33. R. O. Darouiche, R. J. Hamill, S. B. Greenberg, S. W. Weathers, and D. M. Musher, “Bacterial spinal epidural abscess. Review of 43 cases and literature survey,” Medicine, vol. 71, no. 6, pp. 369–385, 1992. View at Google Scholar · View at Scopus
  34. A. Tuchman, M. Pham, and P. C. Hsieh, “The indications and timing for operative management of spinal epidural abscess: literature review and treatment algorithm,” Neurosurgical Focus, vol. 37, no. 2, article E8, 2014. View at Publisher · View at Google Scholar · View at Scopus
  35. G. M. Ghobrial, S. Beygi, M. J. Viereck et al., “Timing in the surgical evacuation of spinal epidural abscesses,” Neurosurgical Focus, vol. 37, no. 2, article E1, 2014. View at Publisher · View at Google Scholar · View at Scopus
  36. W. C. Ziai and J. J. Lewin, “Update in the diagnosis and management of central nervous system infections,” Neurologic Clinics, vol. 26, no. 2, pp. 427–468, 2008. View at Publisher · View at Google Scholar · View at Scopus
  37. D. E. Connor Jr., P. Chittiboina, G. Caldito, and A. Nanda, “Comparison of operative and nonoperative management of spinal epidural abscess: a retrospective review of clinical and laboratory predictors of neurological outcome. Clinical article,” Journal of Neurosurgery: Spine, vol. 19, no. 1, pp. 119–127, 2013. View at Publisher · View at Google Scholar · View at Scopus
  38. C. A. Kauffman, P. G. Pappas, and T. F. Patterson, “Fungal infections associated with contaminated methylprednisolone injections,” The New England Journal of Medicine, vol. 368, no. 26, pp. 2495–2500, 2013. View at Publisher · View at Google Scholar · View at Scopus
  39. O. Adogwa, I. O. Karikari, K. R. Carr et al., “Spontaneous spinal epidural abscess in patients 50 years of age and older: a 15-year institutional perspective and review of the literature: clinical article,” Journal of Neurosurgery: Spine, vol. 20, no. 3, pp. 344–349, 2014. View at Publisher · View at Google Scholar · View at Scopus
  40. W. T. Curry Jr., B. L. Hoh, S. Amin-Hanjani, and E. N. Eskandar, “Spinal epidural abscess: clinical presentation, management, and outcome,” Surgical Neurology, vol. 63, no. 4, pp. 364–371, 2005. View at Publisher · View at Google Scholar · View at Scopus
  41. M. El Sayed and M. D. Witting, “Low yield of ED magnetic resonance imaging for suspected epidural abscess,” The American Journal of Emergency Medicine, vol. 29, no. 9, pp. 978–982, 2011. View at Publisher · View at Google Scholar · View at Scopus
  42. M. L. Noy and S. George, “Unusual presentation of a spinal epidural abscess,” BMJ Case Reports, vol. 2012, 2012. View at Publisher · View at Google Scholar · View at Scopus
  43. A. Prakash, S. Kubba, N. P. Singh et al., “Tuberculous epidural abscess: an unusual presentation,” Indian Journal of Tuberculosis, vol. 51, pp. 157–158, 2004. View at Google Scholar
  44. A. A. Bremer and R. O. Darouiche, “Spinal epidural abscess presenting as intra-abdominal pathology: a case report and literature review,” Journal of Emergency Medicine, vol. 26, no. 1, pp. 51–56, 2004. View at Publisher · View at Google Scholar · View at Scopus
  45. K. L. Ju, S. D. Kim, R. Melikian, C. M. Bono, and M. B. Harris, “Predicting patients with concurrent noncontiguous spinal epidural abscess lesions,” Spine Journal, vol. 15, no. 1, pp. 95–101, 2015. View at Publisher · View at Google Scholar · View at Scopus
  46. D. Rigamonti, L. Liem, P. Sampath et al., “Spinal epidural abscess: contemporary trends in etiology, evaluation, and management,” Surgical Neurology, vol. 52, no. 2, pp. 189–197, 1999. View at Publisher · View at Google Scholar
  47. N. E. Epstein, “Timing and prognosis of surgery for spinal epidural abscess: a review,” Surgical Neurology International, vol. 6, supplement 19, pp. S475–S486, 2015. View at Publisher · View at Google Scholar
  48. T. B. Alton, A. R. Patel, R. J. Bransford, C. Bellabarba, M. J. Lee, and J. R. Chapman, “Is there a difference in neurologic outcome in medical versus early operative management of cervical epidural abscesses?” Spine Journal, vol. 15, no. 1, pp. 10–17, 2015. View at Publisher · View at Google Scholar · View at Scopus
  49. K. Savage, P. D. Holtom, and C. G. Zalavras, “Spinal epidural abscess: early clinical outcome in patients treated medically,” Clinical Orthopaedics and Related Research, no. 439, pp. 56–60, 2005. View at Publisher · View at Google Scholar · View at Scopus
  50. F. Siddiq, A. Chowfin, R. Tight, A. E. Sahmoun, and R. A. Smego Jr., “Medical vs surgical management of spinal epidural abscess,” Archives of Internal Medicine, vol. 164, no. 22, pp. 2409–2412, 2004. View at Publisher · View at Google Scholar · View at Scopus
  51. G. Sengul, A. Akar, F. Alper, and H. Uslu, “Nonsurgically treated cervical brucellar epidural abscess causing spinal cord compression,” Journal of Clinical Neuroscience, vol. 15, no. 12, pp. 1411–1414, 2008. View at Publisher · View at Google Scholar · View at Scopus
  52. J. C. Dombrowski and L. G. Winston, “Clinical failures of appropriately-treated methicillin-resistant Staphylococcus aureus infections,” Journal of Infection, vol. 57, no. 2, pp. 110–115, 2008. View at Publisher · View at Google Scholar · View at Scopus
  53. S. Grewal, G. Hocking, and J. A. W. Wildsmith, “Epidural abscesses,” British Journal of Anaesthesia, vol. 96, no. 3, pp. 292–302, 2006. View at Publisher · View at Google Scholar · View at Scopus
  54. D. E. Connor, P. Chittiboina, G. Caldito, and A. Nanda, “Comparison of operative and nonoperative management of spinal epidural abscess: a retrospective review of clinical and laboratory predictors of neurological outcome,” Journal of Neurosurgery: Spine, vol. 19, no. 1, pp. 119–127, 2013. View at Publisher · View at Google Scholar · View at Scopus
  55. S. S. Lewis and D. J. Sexton, “Metastatic complications of bloodstream infections in hemodialysis patients,” Seminars in Dialysis, vol. 26, no. 1, pp. 47–53, 2013. View at Publisher · View at Google Scholar · View at Scopus
  56. T. Horino, F. Sato, Y. Hosaka et al., “Predictive factors for metastatic infection in patients with bacteremia caused by methicillin-sensitive staphylococcus aureus,” American Journal of the Medical Sciences, vol. 349, no. 1, pp. 24–28, 2014. View at Google Scholar · View at Scopus