Tumor Take Rate Optimization for Colorectal Carcinoma Patient-Derived Xenograft Models

Figure 2

Tumor morphology (20x). Exemplary HE stains from HROC131. (a) Primary tumor; (b) the PDX generated according to the no cooling and (c) the PDX generated according to the 24 h cooling protocol. (b) and (c) are from the cases with the addition of Matrigel. Tumor architecture, growth pattern, and cytological features of the primary tumor are well preserved in the PDX.

(a)

(b)

(c)