Proapoptotic Role of Potassium Ions in Liver Cells

Figure 1

Potassium ions inhibited proliferation and growth of liver cells. L02 cells () and HepG2 cells () were added to 96-well plates cocultured with different concentrations of potassium ions and cultured at different time points (12, 24, and 48 hrs), respectively. We conduct the CCK-8 assay to assess how the potassium ions affected proliferation of L02 and HepG2 cells. (a) The absorbance of L02 cells decreased significantly at 24 hrs and 48 hrs () after culture with potassium ions. (b) The absorbance value of HepG2 cells decreased significantly at 12 hrs and 24 hrs () after being cultured with potassium ions and especially for 48 hrs (). L02 () and HepG2 cells () were added to 6-well plates cocultured with different concentrations of potassium ions and cultured for 48 hrs. (c) The cells number of L02 treated with potassium ions decreased after being cultured for 48 hrs (). (d) The cells number of HepG2 treated with potassium ions decreased significantly after culture for 48 hrs (). All data are represented as mean ± SEM. ; .

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